| Entry |
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|---|
| Name |
Tolfenamic acid (JAN/INN);
Clotam (TN) |
|---|
| Formula |
C14H12ClNO2
|
|---|
| Exact mass |
261.0557
|
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| Mol weight |
261.7036
|
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| Structure |
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| Simcomp |
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| Class |
Anti-inflammatory
DG01504 Nonsteroidal anti-inflammatory drug (NSAID)
DG01911 Anti-inflammatory drug, fenamic acid derivatives
|
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| Remark |
|
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| Efficacy |
Anti-inflammatory, COX inhibitor |
|---|
| Comment |
Fenamic acid derivative
|
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| Target |
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| Pathway |
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| Interaction |
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| Structure map |
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
M MUSCULO-SKELETAL SYSTEM
M01 ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS
M01A ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS, NON-STEROIDS
M01AG Fenamates
M01AG02 Tolfenamic acid
D01183 Tolfenamic acid (JAN/INN)
Drug groups [BR:br08330]
Anti-inflammatory
DG01504 Nonsteroidal anti-inflammatory drug (NSAID)
DG01911 Anti-inflammatory drug, fenamic acid derivatives
D01183 Tolfenamic acid
Target-based classification of drugs [BR:br08310]
Enzymes
Oxidoreductases (EC1)
Prostaglandin synthase
PTGS1 (COX1)
D01183 Tolfenamic acid (JAN/INN)
PTGS2 (COX2)
D01183 Tolfenamic acid (JAN/INN)
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| Other DBs |
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| KCF data |
ATOM 18
1 C8x C 14.4187 -16.5148
2 C8x C 14.4187 -17.9143
3 C8x C 15.6307 -18.6140
4 C8x C 16.8427 -17.9143
5 C8y C 16.8427 -16.5148
6 C8y C 15.6307 -15.8150
7 C8x C 19.2668 -17.9143
8 C8y C 19.2668 -16.5148
9 N1b N 18.0548 -15.8150
10 C8x C 20.4789 -18.6140
11 C8x C 21.6909 -17.9143
12 C8y C 21.6909 -16.5148
13 C8y C 20.4789 -15.8150
14 C6a C 15.6307 -14.4157
15 O6a O 14.4019 -13.7060
16 O6a O 16.8258 -13.7255
17 X Cl 22.9069 -15.8127
18 C1a C 20.4790 -14.4203
BOND 19
1 1 2 2
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 2
6 1 6 1
7 7 8 1
8 8 9 1
9 5 9 1
10 7 10 2
11 10 11 1
12 11 12 2
13 12 13 1
14 8 13 2
15 6 14 1
16 14 15 2
17 14 16 1
18 12 17 1
19 13 18 1
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